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boston harbor, weight loss, problems, fat girls , treats cellulite, joint pain, downeast, fat, arms, inflatable, leptin, dr. coleman, triton, | The effect advice of fat on inflammation is just half of the cycle. The effects of inflammation on fat are equally intense. When inflammation is severe, as in a life-threatening infection, it can cause tremendous weight loss. With severe inflammation, the body cannibalizes itself and both fat and muscle cells are destroyed. This is not a good way to lose weight. The breakdown of muscle is always greater than the breakdown of fat. advice When inflammation is mild and chronic, producing few symptoms and only subtle changes on blood tests, inflammation has a very different effect advice on your metabolism. Chronic low-grade inflammation makes your brain and body resistant to the normal regulatory effects of leptin and other hormones, including insulin and cortisol. Insulin and cortisol are not adipokines. |
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TNF interferes with the operation of insulin, and fat girls is therefore fat girls a major contributor to insulin resistance. So, fat girls too, is another adipokine called resistin. What we see in obesity is the swelling of fat tissue accompanied by a cacophony of cellular activity, most of it pushing the body toward a state of excess inflammation. Among the pro-inflammatory substances made by fat cells themselves are leptin, TNF, IL-6, and resistin. Add the contribution of fat-embedded macrophages and their own payload of TNF and IL-6, and biologists are beginning to view fat as a brewery of inflammatory chemicals. The whole body is affected by this state of affairs, since inflammatory activity is not limited to fat tissue but spills over into the bloodstream. Thus, overweight people become subject to a body-wide state of chronic, low-grade inflammation, induced by fat itself. |
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