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| boston harbor, weight loss, problems, fat girls , treats cellulite, joint pain, downeast, fat, arms, inflatable, leptin, dr. coleman, triton, | The plot gets even thicker. The inflammatory nature of fat is not only due to fat cells themselves. In addition to fat cells (adipocytes), fat also contains blood vessels and white blood superfoods cells. Fat specifically attracts a type of white blood cell called a macrophage. Macrophage literally means "large eater" and macrophages are large white blood cells that gobble up cellular debris. They are scavengers, sometimes called "garbage men of the immune system." The macrophages found in fat superfoods are major producers of inflammatory mediators, especially a substance called Tumor Necrosis Factor (TNF). TNF is well-known in medicine, because high levels of it produce much of the tissue damage and pain associated with rheumatoid arthritis and other autoimmune diseases. |
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| So the relationship between obesity and osteoarthritis is not just created by how much you weigh. It is a hormonal relationship in which the body’s normal homeostatic mechanisms go awry and produce disease. Everyone experiences trauma to weight loss their knees during the course of their lives. Lean people, like athletes, who weight loss experience extensive, repetitive trauma, are at risk for osteoarthritis because the stimulus to inflammation and counter-inflammation is so intense. People who are weight loss overweight develop osteoarthritis because excess body fat causes an excessive inflammatory response to minor injury, which then triggers an increase in the counter-inflammatory response. The result is that both inflammatory and anti-inflammatory mediators are increased in obesity. The end result is no longer homeostasis but disease, which develops because of the unbridled activity of chemical mediators that fail in their effort to heal. |
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