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The analysis revealed out patient procedure that NSAIDs can reduce short term pain slightly better than placebo, but it does not support long term use of NSAIDs for this condition. The advantage of oral NSAIDs over placebo for short term pain relief is small and probably clinically insignificant. "As use of oral NSAIDs may incur serious adverse effects, they can only out patient procedure be recommended for limited use in osteoarthritis of the knee," the researchers concluded. Using topical NSAIDS to relieve the pain of osteoarthritis is only beneficial for the first two weeks, found another out patient procedure study available on bmj.com. Topical NSAIDS were superior to placebo in relieving pain due to osteoarthritis only in the first two weeks of treatment. Trials lasting four weeks showed no benefit. A similar pattern was found for mobility and stiffness.
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